University of Natural Resources and Applied Life Sciences (BOKU), Vienna, Department of Biotechnology
Cornelia Kasper studied Chemistry at the University Hannover and received her Diploma degree 1994. She performed her phD thesis at the Institute for Technical Chemistry 1995-1998 on: “Purification of proteins and other biological active compounds using novel chromatographic approaches”.
She was employed as EU liason officer at the University of Hannover 1998-2000. Afterwards she received a Habilitation-fellowship from the University of Hannover 2000-2006. She finished her Habilitation on “New approaches in cell culture techniques”and received the Venia legendi “Technische Chemie” in 2007.
2000-2011 Cornelia Kasper has been head of Cell Culture and Tissue Engineering Group at the Institute for Technical Chemistry, Leibniz University of Hannover. Furthermore she was head of young researcher group JRG “Large Scale Cultivation” within Cluster of Excellence “Rebirth” (from Regenerative Biology and Reconstructive Therapies).
Since October 2011 Cornelia Kasper has been appointed as full University Professor “Biopharmaceutical Technology and Products” at the Department of Biotechnology at Boku.
Current Research Activities
Cells as product – tissue engineering
- Development of bioreactor systems for tissue engineering applications (including systems for the application of mechanical strain/load)
- Isolation, expansion and directed differentiation of stem cells from different sources (e.g. fat tissue, umbilical cord)
- Investigation and optimization of different culture conditions (e.g. hypoxia, medium composition)
- Isolation and investigation of subpopulations
- Tissue engineering (musculoskeletal tissues, peripheral nerve) under defined and controlled conditions including biophysical stimulation
- Establishment of co-culture systems (e.g. MSC and EPC)
- Functionalization of biomaterials (e.g. surface decoration, incorporation of microspheres as controlled release systems)
Cells as producers
- Production and isolation of proteins and growth factors (e.g. FGF, LIF, antibodies)
- Use of stem cells for production of “natural” cytokines and extracellular matrix proteins
Cells as sensors
Application of cell culture technology for “biological testing” using cell based assays (e.g. biological active compounds, nanoparticles)
Study of effects of hydrodynamic forces and mechanotransduction
EU- Expert for Framework Programme FP 6 and 7 proposals
- Tissue Engineering
- Journal of Biotechnology
- Journal of Tissue Engineering and regenerative Medicine
- Applied Microbiology and Biotechnology
- Journal of Biomedical Materials Research
- Volume Editor “Advances in Biochemical Engineering/ Biotechnology” Springer Verlag
- Volume 112: “Bioreactors for Tissue Engineering I” (2009)
- Volume 123: “Bioreactors for Tissue Engineering II” ( 2010)
- Volume 126: “Tissue Engineering III: Cell Substrate Interaction in Tissue Culture” (2012)
- In press (two volumes): “Mesenchymal stem cells – from Basics to Clinical Applications” (I + II)
- DECHEMA Gesellschaft für Chemische Technik und Biotechnologie e. V. (Society for Chemical Engineering and Biotechnology), appointed member of "Cell Culture Technology"
- Termis (appointed member of EU chapter counsel)
- International Society for Cellular Therapy ISCT