TC-3 bioreactor

  • Overview
  • Specifications
  • Accessories
  • Images and videos
  • Downloads

The TC-3 Bioreactor has been designed as a simple, easy-to-use system suitable to create cell culture experimental set-ups accounting for user-defined mechanical loading profiles. The needs of researchers who would like to culture cells under mechanical stimuli have been accounted for in the design of the TC-3. It combines the features of a traditional testing machine with the particular demands of cell culture, with special emphasis on the sterilization of the parts which are going to contact the culture medium, the easy assembling, the sample inspection by microscopy techniques and the straightforward sample manipulation.

The TC-3 permits to work with:

  • Horizontally and vertically arranged multiple samples.
  • Immersed and air-liquid interface setups.
  • Sheet-shaped, rod-shaped and cylinder-shaped substrates.
  • Tension and compression axial loading.
  • Simultaneous flow and deformation conditions.
  • Hydrostatic pressure conditions.

Depending on the scaffold type, it is also possible to use microscopy techniques to inspect the status of the culture in-situ.

Scalability and versatility are key features of the TC-3, in which three grips models can be interchanged in order to adapt to the features of the testing substrate or scaffold.

The system is controlled by a simple computer interface which allows defining the most common loading profiles which can be applied on the culture substrate.


tc3 vertical front
TC-3 load bioreactor system.


The table below shows the main technical specifications of the EBERS TC-3 Mechanical Stimulation Bioreactor.

TC-3 Bioreactor technical sheet

TC-3 Mechanical Stimulation Bioreactor
Actuation system
Dimensions [W x D x H]
  • Vertical configuration: 285 x 478 x 110 mm
  • Horizontal configuration: 290 x 300 x 492 to 512 mm
Number of chambers Up to 3
Minimal displacement increment 0.005 mm
Maximal force 400 N
Control PC-based control software
Power supply and consumption 110-220 V, 50-60 Hz, IEC 14 power cord
Maximal deformation rate 10 mm/s
Tension and Compression Chambers
Autoclavable Yes
External dimensions [W x D x H] 78 x 137 x 51 mm
Internal dimensions [W x D x H]  38 x 65 x 32 mm
Maximal internal volume [*]   ~ 90 ml
  • Sheet-like grips
Autoclavable Yes
Useful width 35 mm
Maximal displacement 31 mm
Minimal displacement 1 mm
  • Rod-like grips
Autoclavable Yes
Useful width 30 mm
Maximal displacement 30.5 mm
Minimal displacement 0.5 mm
  • Compression grips
Autoclavable Yes
Useful diameter [mm] 22 mm
Maximal displacement [mm] 30.5 mm
Minimal displacement 0.5 mm
Tension-Compression and Flow Chambers
Autoclavable Yes
External dimensions [W x D x H] 78 x 137 x 51 mm
Internal dimensions [W x D x H]  38 x 65 x 32 mm
Maximal internal volume [*]   ~ 90 ml
  • Tension-Flow grips for tubular scaffolds
Autoclavable Yes
Scaffold diameter 1.65 to 6.35 mm
Maximal displacement 23 mm (for the 1/16" connector)
Minimal displacement 0 mm
  • Compression-Flow grips for porous scaffolds
Autoclavable Yes
Maximal scaffold diameter 10, 13 and 18 mm
Maximal displacement 25 mm
Minimal displacement 0 mm
Hydrostatic Pressure Chamber
Autoclavable Yes
External dimensions [W x D x H] 80 x 137 x 83 mm
Internal dimensions [W x D x H]  40 x 45 x 46 mm
Internal volume  ~ 80 ml
Maximal pressure 4 bar

Please contact us for further information if you want to know more about the TC-3.



Anchoring systems

Adjustable anchoring system

Adjustable anchoring system

This anchroing system allows to customize the length of the chamber shaft in order to adapt it to the length of the scaffold. Thereby, the deformation conditions can be adjusted when working with different length scaffolds or to obtain homogenous conditions when working with the hydrostatic pressure chambers. It is comaptible with all the chambers and grips available.


Single sample tension & compression


Tension & compression chambers

Culture chambers are designed to be compatible with all the available deformation grips.

rodlike grips

Rod-like scaffolds grips

Apply tension loads on cylindrical or sheet-like scaffolds.

compression grips

Compression grips

Apply compression loads on your scaffolds.

membrane grips

Sheet-like scaffolds grips

Apply tension loads to membranes or sheet-like substrates.


Multiple sample tension & compression

20cavities 80

Multi-cavity 20 samples tension & compression chamber

Up to twenty samples subjected to the same tension and/or compression loads.

tension 80

Tension grips for the multi-cavity chamber 

Grips suitable for the application of simultaneous tension loads on multiple sample.

compression 80

Compression grips for the multicavity chamber

Grips designed for the application of compression loads simultaneously on multiple samples.


Tension, compression and flow

tension-compresion and flow chamber

Tension-compression & flow chamber

This chambers allows applying flow through the pores of your scaffold while subjected to compressive loads and flow thorugh the lumen of your tubular scaffold when subjected to tension loads.

compression-flow grips

Flow and compression grips

Apply perfusion through the pores of your scaffold while subjecting it to compressive loads.

flow-tension grips

Flow and tension grips

Use this set of grips to create tension conditions on your sample while subjected to luminal flow.


Hydrostatic pressure


Hydrostatic pressure chamber

Apply up to 4 bar of hydrostatic pressure to your samples using the TC-3 system.


Electrical stimulation


Electrical stimulation module

Create coordinated electrical and mechanical stimulation conditions.




Technical specifications